The Texans started their second half in impressive fashion.
A 15-play, 79 yard drive burned 8:21 off the clock and culminated in a Deshaun Watson 5-yard touchdown run.
The score gave the Texans a 28-10 advantage with 6:39 left in the third quarter.
Houston faced a third down just once on the possession, as Watson and the Texans deftly mixed up runs and passes and kept the Colts off balance.
Running back Lamar Miller had gains of six and seven yards on the series, while Watson found Keke Coutee three different times for a total of 31 yards, and DeAndre Hopkins once for 13 yards.
The Houston Texans are pumped and ready to take on the Colts at Lucas Oil Stadium.