The Patriots tumbled to a third place AFC East finish in 2020, as they went 7-9.
Bill Belichick enters his 22nd season as the Patriots head coach, and he's guided New England to six Super Bowl victories, and three Super Bowl appearances.
Houston triumphed over the Patriots last season at NRG Stadium, winning a Week 11 showdown by a 27-20 margin. It was the second straight Texans' victory over New England. In all, the franchises have met 11 times in the regular season.
Notable Patriots: QB Mac Jones, CB Stephon Gilmore, QB Cam Newton, LB Kyle Van Noy, TE Jonnu Smith
Executive vice president, football operations Jack Easterby worked for the Patriots from 2013-2018.
WR Brandin Cooks spent the 2017 season with New England. CB Keion Crossen's rookie season of 2018 was with the Patriots. OL Marcus Cannon spent the first nine seasons of his career (2011-2019) with the Patriots.