Despite holding a 20-13 lead in the fourth quarter, the Texans tumbled to the Raiders on Monday Night Football, losing 27-20.
In the aftermath, Houston credited Oakland with the victory, but pointed to what might have been.
"It's very tough," defensive end Jadeveon Clowney said. "We should've won this game. I'm still going to say that: we should've won. We gave this one away. It slipped through our hands."
Nick Novak's 29-yard field goal with 10:57 remaining in the contest gave Houston a touchdown advantage.
But 13 seconds later, the Raiders answered with a 75-yard scoring strike from Derek Carr to Jamize Olawale to equalize it. With 4:43 left, a Carr-to-Amari Cooper 35-yard touchdown pass gave the Raiders what would be the deciding score.
"It's very tough because we thought we had this one," cornerback A.J. Bouye said. "We didn't keep our foot on the pedal. They're a great team and they played a full 60 minutes."
For tight end Ryan Griffin, Monday's loss was especially disappointing because of the way the offense was able to operate.
"We dominated the ball on the offensive side," Griffin said. "We moved at will. We didn't get the spots there at the end. Tough. Tough."
Outside linebacker Whitney Mercilus said the defeat "hurts", but that the Texans have refocus on a San Diego Chargers club that heads to NRG Stadium this Sunday.
"We gotta turn the page and move on," Mercilus said.
The Texans are now 6-4 in 2016.
Texans fans showed up to watch their favorite team take on the Raiders in Mexico City.