Houston Texans
| Player | Injury | WED |
|---|---|---|
| Nico Collins | Concussion | DNP |
| Christian Kirk | Hamstring | DNP |
| Denico Autry | Knee | LP |
| Derek Barnett | Ankle | LP |
| Brenden Bates | Wrist | LP |
| Dalton Schultz | Back / Shoulder | LP |
| Jaylin Smith | Hamstring | LP |
| Alijah Huzzie | Knee | FP |
San Fransisco 49ers
| Player | Injury | WED |
|---|---|---|
| Jake Brendel | Hamstring | DNP |
| Yetur Gross-Matos | Knee / Hamstring | DNP |
| Bryce Huff | Hamstring | DNP |
| Deommodore Lenoir | Quadricep | DNP |
| Christian McCaffrey | Not Injury Related - Resting Player | DNP |
| Ricky Pearsall | Knee | DNP |
| Trent Williams | Not Injury Related - Resting Player | DNP |
| Spencer Burford | Knee | LP |
| Luke Gifford | Hamstring | LP |
| Renardo Green | Toe | LP |
| Brock Purdy | Toe | LP |
| Upton Stout | Ankle | LP |
| Kalia Davis | Hand | FP |
| Jauan Jennings | Ankle / Rib / Shoulder | FP |
| Mac Jones | Knee / Oblique | FP |
| C.J. West | Thumb | FP |
Practice Status
- DNP - Did not participate in practice
- LP - Limited participation in practice
- FP - Full participation
- (-) - Not listed
Game Status
- Out - Player will not play
- Doubtful - Player is unlikely to play
- Questionable - Player is not certain to play
- (-) - Not listed
