Brian Hoyer won't play against the Jets on Sunday, and T.J. Yates will be the starting quarterback.
Head coach Bill O'Brien ruled the starting signal caller out after Friday afternoon's practice.
Hoyer left Monday night's win over the Bengals late in the third quarter and has been going through the concussion protocol. He didn't practice on Wednesday, Thursday or Friday with the Texans.
O'Brien did say, however, he's optimistic Hoyer will return to practice and play next week.
It's the first reglular season start for Yates since Week 17 of the 2011 season.
He tossed a touchdown to DeAndre Hopkins in the fourth quarter of the win at Cincinnati, and completed 45.5 percent of his passes for 69 yards.
Yates and the Texans kick off against the Jets at noon on Sunday in NRG Stadium.
The Houston Texans roster in photos.
DL Mario Addison, #56 (AP Photo/Butch Dill)
QB, Kyle Allen, #3
RB, Darius Anderson, #30
DB, Grayland Arnold, #35
TE, Antony Auclair, #83
DL, Ross Blacklock, #90
DL, Thomas Booker, #96
OL, Justin Britt, #68
DB, Terrence Brooks, #8
TE, Pharaoh Brown, #85
RB, Rex Burkhead, #28
WR, Jalen Camp, #17
OL, A.J. Cann, #60
LB, Blake Cashman, #53
DL, Maliek Collins, #97
WR, Nico Collins, #12
WR, Chris Conley, #18
WR, Brandin Cooks, #13
TE, Darrell Daniels, #47 (AP Photo/Stephen Brashear)
WR, Davion Davis, #14
LB, Tae Davis, #19
OL, Austin Deculus, #76
WR, Phillip Dorsett, #4
QB, Jeff Driskel, #6
DL, Michael Dwumfour, #98
WR, Drew Estrada, #81
K, Ka'imi Fairbairn, #7
DB, Jacobi Francis, #38
RB, Royce Freeman, #26
OL, Carson Green, #62
DL, Jonathan Greenard, #52
WR, DaeSean Hamilton, #5
OL, Kenyon Green, #59
DL, Rasheem Green (AP Photo/Daniel Kucin Jr.)
LB, Kamu Grugier-Hill, #51
LB, Christian Harris, #48
DL, Demone Harris, #94
WR, Damon Hazelton, #86
OL, Charlie Heck, #67
LB, Neville Hewitt, #43
QB, Kevin Hogan, #16 (AP Photo/Stew Milne)
OL, Tytus Howard, #71
DL, Jerry Hughes, #55 (AP Photo/Adrian Kraus)
FB, Andy Janovich, #41
An image from the Aug. 21, 2021 Houston Texans preseason game 2 against the Dallas Cowboys at AT&T Stadium. The Texans won 20-14.
WR, Johnny Johnson III, #89
P, Cameron Johnston, #11
TE, Brevin Jordan, #9
DB, Desmond King II, #25
LB, Christian Kirksey, #58
DL, Roy Lopez, #91
RB, Marlon Mack, #2
DB, Tristin McCollum, #39
OL, Justin McCray, #64
WR, John Metchie III, #88
QB, Davis Mills, #10
WR, Chris Moore, #15
OL, Jimmy Morrissey, #79
DB, Eric Murray, #23
DB, Steven Nelson (AP Photo/Matt Rourke)
DB, Steven Nelson, #21
DL, Adedayo Odeleye, #75
OL, Cedric Ogbuehi, #77
RB, Dare Ogunbowale, #33
DL, Ogbonnia Okoronkwo, #45
DB, Jonathan Owens, #36
RB, Dameon Pierce, #31
LB, Kevin Pierre-Louis, #57
DB, Jalen Pitre, #42
FB, Paul Quessenberry, #45
OL, Scott Quessenberry, #54
TE, Teagan Quitoriano, #84
LB, Jalen Reeves-Maybin, #34 (AP Photo/Lon Horwedel)
DL, Derek Rivers, #95
OL, Max Scharping, #74
DB, Kendall Sheffield (AP Photo/Kevin Sabitus)
DB, Tremon Smith, #24
OL, Jordan Steckler, #70
DB, M.J. Stewart, #29
DB, Derek Stingley Jr., #24
DB, Tavierre Thomas, #37
OL, Laremy Tunsil, #78
LB, Garret Wallow, #32
WR, Connor Wedington (AP)
LS, Jon Weeks #46
DB, Isaac Yiadom, #20
