T.J. Yates left with an injury in the second quarter of the game at Indianapolis.
On a scramble in Colts territory, Yates dove head forward and was clutching his left leg. He stayed on the ground for a few moments, and then walked off the field and to the locker room.
Brandon Weeden entered the contest with 1:14 reamining and completed 4-of-5 passes for 36 yards on the half-closing drive. Nick Novak kicked a 22-yard field goal as time expired, and the Texans went to the locker room trailing 10-3.
Yates left with 68 passing yards on 6-of-10 completions, with one interception. He was also sacked twice.
The Houston Texans roster in photos.