The Texans fell to 3-2 on Sunday with a loss at Minnesota, but on Monday they'd set their focus elsewhere.
"I told the team that this morning, the first thing I do is look in the mirror and that's what I'm trying to do," head coach Bill O'Brien said. "Look in the mirror and try to get better and figure out what we need to do to play a lot better against the Colts."
The Texans and Colts split last season's home-and-home matchup, as the road team was victorious each time. Andrew Luck and company come to NRG Stadium for the Sunday night matchup, and wide receiver
DeAndre Hopkins said the Texans mindset is all about the Colts.
"We're number one in our division right now," Hopkins said. "Big game this week against the Colts and that's what we're focusing on. It's a long season. We've got a lot to fight for. We've got a lot of tough guys in here. Nobody's head is down."
Indianapolis is 2-3, fresh off a home win over the Chicago Bears. They've not lost in Houston since 2012. All three of the Texans wins this season have been at home, and they're aiming for number four on Sunday evening.
"This game's big," tight end C.J. Fiedorowicz said. "We've been playing well at home. We've gotta drop this last (Minnesota) game."
Kickoff is set for 7:30 p.m. CT.
The Texans faced the Vikings in a week 5 matchup at U.S. Bank Stadium.